COMPARISON OF INHIBITORY ACTIVITIES OF META AND PARA SUBSTITUTED N-ARYL 3-HYDROXYPYRIDIN-4-ONE MANNOSIDES TOWARDS TYPE 1 FIMBRIATED E. COLI

Comparison of Inhibitory Activities of meta and para Substituted N-aryl 3-Hydroxypyridin-4-one Mannosides Towards Type 1 Fimbriated E. coli

In uropathogenic Escherichia coli, Pot Grab mannose-specific adhesion is mediated by the FimH adhesin located at the tip of type 1 fimbriae.Novel mannosylated N-aryl substituted 3-hydroxypyridin-4ones with meta substituents on the aryl part of the molecule were prepared, and their inhibitory properties towards the adhesion of E.coli to guinea pig e

read more

Acute Onset Collagenous Colitis with Unique Endoscopic Findings

We experienced a rare case of 72-year-old woman with acute onset collagenous colitis (CC) induced by lansoprazole.The patient developed acute abdominal pain, watery diarrhea, and melena that are quite rare in usual CC.We could find the characteristic colonoscopic Collections findings such as active long liner ulcers in the patient.We also observed

read more